In budget impact analysis, “uptake” refers to the rate at which a new technology is adopted and utilized by eligible patients over time. This concept is crucial when comparing a hypothetical future scenario (approval of a new technology) against a counterfactual (no approval).

Key points about uptake include:

– Definition: Uptake is the proportion of eligible patients who receive the new technology in each consecutive year after its introduction.

– Gradual Increase: Uptake often starts slowly with a low percentage of patients and gradually increases over time.

– Considerations: It is important to consider whether the technology will be provided to new (incident) patients, existing (prevalent) patients, or both. This affects how quickly and broadly the technology is adopted.


– If a new drug is approved, the uptake might be modeled to start at 10% of eligible patients in the first year, increasing to 50% by the fifth year. This gradual increase reflects the time needed for the drug to become widely accepted and integrated into clinical practice.


– Realistic Projections: Considering uptake provides a more realistic projection of the budget impact over time, rather than assuming immediate and universal adoption.

– Policy Planning: Helps policymakers and budget planners anticipate the financial implications of introducing new technologies.


– Data Availability: Accurate estimation of uptake rates can be challenging due to limited data on how quickly new technologies are adopted.

– Variability: Uptake rates can vary significantly based on factors like healthcare provider acceptance, patient demand, and marketing efforts.

Understanding and modeling uptake is essential in budget impact analysis to provide accurate and realistic estimates of the financial implications of new healthcare technologies.